For the first time, Geneva will host the European Conference on Computational Biology (ECCB) in 2026, following the recent ECCB 2024 conference held in Finland. SIB, the Swiss Institute of Bioinformatics, was chosen from among five European institutions to organize this major event, which will take place from 31 August to 4 September 2026. The conference will draw over a thousand scientists and experts from across Europe to explore the latest advances and challenges in the analysis and management of biological data. This high-caliber program will not only showcase cutting-edge discoveries but also highlight the far-reaching impacts of computational biology—a field with immense potential yet still little known to the general public.