The 10th International Conference on System Modeling and Optimization will be held in Munich, Germany on February 10-12, 2022. The aim of ICSMO is to povide a platform for researchers, engineers, academics as well as industry professionals from all over the world to present their research results and development activities in the area of System Modeling and Optimization. This conference provides opportunities for delegates to exchange new ideas and research findings in a face to face environment, to establish business or research relationships and to find global partners for future collaboration.